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Thirai Sorgam > Diabetes > Your Questions About Ozempic Answered by an Endocrinologist
Diabetes

Your Questions About Ozempic Answered by an Endocrinologist

March 26, 2025 4 Min Read
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As Ozempic continues to grow in popularity, so are questions surrounding its use, benefits and potential side effects.

We asked endocrinologist Anne Peters, director of the clinical diabetes program at Keck School of USC, the most common question about othempics in highly diabetic communities.

Are Ozempic and Wegovy the same medicine? Can I switch between the two?

Because Ozempic and Wegovy are the same drug (Semaglutide), the answers to the following questions are related to both brands:

Semaglutide functions by mimicking the action of the hormone glucagon-like peptide 1 (GLP-1), stimulates the pancreas to produce more insulin. When insulin increases, sugar enters the cells and lowers blood sugar levels.

The main reason semaglutide is effective in weight loss is to increase satiety and reduce appetite.

Is Ozempic the most effective medicine for weight loss?

Semaglutide (Ozempic & Wegovy) is very effective in weight loss, but there are other options available.

Studies show that people taking Ozempic have an average weight loss of 10-15%.

In comparisonclinical trials showed that people taking Tylezatide (Zepbound and Munjaro) lost an average of 20% TThe heir’s weight.

Another difference between Ozempic and Tylezatide is that Ozempic is approved by the FDA to reduce the risk of heart attacks and stroke in people with type 2 diabetes, but Tylezatide is not.

For more information, see Ozempic vs. Mounjaro: Which should I choose?

Do I need to stay in Ozempic forever, or can I stop after losing weight and defeating A1c?

You should maintain your medication as long as you see good results and tolerate it without side effects. The medication only works as long as you are taking it.

See also  The Best CGM Placements (and How to Keep Your CGM On)

What happens if I stop taking Ozempic?

Always consult your doctor before stopping prescription medication. There must be plans to gradually reduce the dose and alternative ways to manage the condition that the medication is being treated.

How common are Ozempic side effects?

Some of the most common side effects of Ozempic include:

  • nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • constipation

These common side effects are often seen only during the first few weeks and increased doses after starting Ozempic.

The rare but serious side effects of Ozempic are:

  • Thyroid tumor
  • Pancreatitis
  • Changes in your vision.
  • Hypoglycemia (hypoglycemia).
  • worsening kidney problems and kidney failure.
  • Serious allergic reactions.

If you experience side effects using Ozempic, we recommend reporting them to the FDA through the MedWatch program.

How can I avoid side effects?

Starting with a low dose and increasing it gradually can avoid or minimize many of the most common side effects.

Are there any allergic reactions to Ozempic?

Who should not take Ozempic?

Ozempic is also not recommended if you are pregnant, under the age of 18, or have a history of diabetic retinopathy.

How does Ozempic affect mental health?

Can people with type 2 diabetes take Ozempic and metformin together?

Do you think Ozempic is useful for people with type 1 diabetes who don’t need to lose weight?

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